ORIGINAL ARTICLE
Stress hormone response to various anaesthetic
techniques during thyreidectomy
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Department of Anaesthesiology and Intensive Therapy, Medical University of Białystok
Publication date: 2019-09-11
Anaesthesiol Intensive Ther 2012;44(1):4-7
KEYWORDS
ABSTRACT
Background:
Thyroidectomy is among the most frequently performed procedures in endocrine
surgery. The hormonal response to surgery and anaesthesia depends in part on the anaesthetic
techniques used; therefore, we measured serum concentrations of TSH, fT4, and fT3 in patients
scheduled for elective thyroidectomy under TIVA or VIMA.
Methods:
Seventy-eight adult patients, of both sexes, with non-toxic or hyperthyroid nodular
goitre, were divided into groups with regard to the goitre type and the technique of anaesthesia
used during thyroid surgery. Serum concentrations of TSH, fT4, and fT3, were measured and the
surgical stress was estimated using the E-PASS scale.
Results:
In the groups examined, the mean serum concentrations of TSH remained unchanged
during the period of observation. The initially high fT4 and fT3 concentrations gradually decreased,
reaching their lowest level on the fourth day after surgery.
Conclusion:
Both VIMA and TIVA can be regarded as safe techniques of anaesthesia for
thyroidectomy.